Pfizer is expanding the recall of its anti-smoking drug Chantix (varenicline), the company announced Friday.
The nationwide recall of all Chantix 0.5 mg and 1 mg tablets was prompted because they may contain levels of a nitrosamine, N-nitroso-varenicline, that are at or above levels approved by the U.S. Food and Drug Administration.
Long-term ingestion of N-nitroso-varenicline may b...
The anesthesia drug ketamine and a related medicine called esketamine appear to be safe for tough-to-treat depression, researchers report.
A number of studies have suggested that low doses of ketamine, which is also abused as a club drug under monikers that include "K" and "Special K," provide rapid antidepressant effects, typically improving mood within 24 hours to seven days.
Accidental exposure to fentanyl pain patches is putting children's lives at risk, the U.S. Food and Drug Administration warns.
Fentanyl is a powerful opioid pain reliever; so powerful that fentanyl patches are typically only prescribed to patients who require round-the-clock, long-term pain relief, such as cancer patients. They're generally replaced every three days.
Giving high doses of buprenorphine in the emergency department is a safe and effective way of treating withdrawal symptoms in patients battling opioid addiction, according to a new study.
"Emergency departments are at the front lines of treating people with opioid use disorder and helping them overcome barriers to recovery such as withdrawal," said Dr. Nora Volkow, director of the U.S. Na...
A longer prison sentence has been handed to the founder of a now-closed Massachusetts pharmaceutical facility responsible for the 2012 meningitis outbreak that killed 100 people and sickened hundreds of others.
Barry Cadden, who was president and co-owner of the New England Compounding Center (NECC), received a 14-and-a-half year sentence from a federal judge Wednesday.
You're getting no real benefit from taking weight-loss supplements like garcinia cambogia, green tea extract, glucomannan, conjugated linoleic acid or chitosan, two new reviews show.
Most of the clinical trials studied didn't show these supplements producing any weight loss among users, the researchers said. In the rare cases where people did lose weight, they didn't drop enough pounds to...
Nearly one-third of seniors who take thyroid hormone also take drugs known to interfere with tests of thyroid function, a new study finds.
It's common for older adults to take a thyroid hormone (levothyroxine) to treat low levels of natural thyroid hormone. But tests used to determine the dose and effectiveness of treatment can be affected by other medications, including prednisone, predn...
Researchers report that insulin can be stored at less-cold temperatures than previously known, potentially simplifying diabetes care for people in warmer regions that have fewer resources.
Researchers from Doctors Without Borders and the University of Geneva tested insulin storage in real conditions ranging from 77 to 98.6 degrees Fahrenheit for four weeks -- the time it typically takes t...
Marijuana packs a lot more punch than it did 50 years ago, making it a greater threat to health, researchers say.
"As the strength of cannabis has increased, so too has the number of people entering treatment for cannabis use problems," said study co-author Tom Freeman, director of the addiction and mental health group at the University of Bath in England.
For at least two decades, the U.S. Food and Drug Administration has been approving new formulations of prescription opioids without requiring drug manufacturers to gather important information on safety and effectiveness, a new study claims.
The FDA approved dozens of these highly addictive medications for treatment of chronic pain between 1997 and 2018 based on clinical trials that:<...
Seniors who take depression and anxiety drugs shouldn't be prescribed opioid painkillers by their dentist because it puts them at increased risk for problems, researchers warn.
They analyzed 2011-15 dental and medical data for 40,800 patients aged 65 and older across the United States. There were 947 emergency room visits and hospitalizations in the 30 days after a dental visit.
The narcolepsy medicine modafinil doesn't appear to increase the risk of birth defects, according to a new study that contradicts earlier research.
"This study is based on twice as many pregnancies as earlier studies, and we find no increase in the risk of malformation in infants exposed to modafinil during pregnancy," lead author Carolyn Cesta, of the Karolinska Institute in Sweden, ...
Taking the statin Crestor in combination with the diabetes drug canagliflozin (Invokana) may have the potential to trigger statin toxicity, a new case report suggests.
Although this report details the problem in just one woman, the researchers noted concern because these drugs are taken by millions of people worldwide. These drugs are also increasingly prescribed together.
People taking a class of diabetes medications called SGLT2s have up to three times the risk for a serious complication called diabetic ketoacidosis (DKA) compared to people taking another drug, new research reveals.
SGLT2 (sodium-glucose cotransporter-2) inhibitors -- such as Farxiga, Jardiance and Invokana -- are a newer type of oral diabetes medicine. This class of medications is k...
You suddenly break out in a rash or your throat gets scratchy. You assume you're allergic to something … maybe pollen or a detergent. But could you be allergic to something in your food or medicine, and how could you tell?
The medical community disagrees as to whether additives in food or even medications -- such as dyes, preservatives or emulsifiers -- cause true allergic reac...
New warnings about the risk of dangerous breathing difficulties when gabapentinoids are used with opioids or by certain patients must now appear on product labels, the U.S. Food and Drug Administration announced Thursday.
Serious breathing problems that can lead to death can occur in patients who use gabapentinoids with prescription opioid painkillers or other drugs that depress the c...
Millions of Americans think they're allergic to penicillin, but they're not, a new study reveals.
This erroneous belief adds millions of dollars to health care costs and results in unnecessary side effects from more powerful antibiotics, researchers say. It also adds to the danger of creating antibiotic-resistant bacteria, they warn.
Large pills and dietary supplements can be tough for anyone to swallow, but new research finds they may pose a potentially dire risk to seniors.
A study from the U.S. Food and Drug Administration found that between 2006 and 2015, almost 4,000 people had trouble swallowing dietary supplements that was serious enough to report. Three people died after choking on them.
Americans could import less expensive prescription drugs from Canada under a plan being developed by the Trump administration.
"Driving down drug prices requires a comprehensive approach and we must continue to look at all innovative solutions to this challenge," U.S. Health and Human Services Secretary Alex Azar said in an HHS news release Wednesday.
Easing chronic pain is the main reason Americans use medical marijuana, a new study finds.
"We wanted to understand the reasons why people are using cannabis medically, and whether those reasons for use are evidence-based," said lead author Kevin Boehnke. He's an investigator at University of Michigan's Chronic Pain and Fatigue Research Center.
Would you stop taking a medication if you heard a negative news story about it?
Sticking with a prescription drug regimen, or "medication adherence," is already a challenge for many patients, with not taking medications as prescribed being a key reason people struggle to control chronic conditions. Adding to the problem, according to a Danish study, is that negative reports in the med...